Method development and data collection by LC-MS/MS, and other modalities (Absorbance/Fluorescence)
Supporting new assay development for ADME activities
Analyzing data from enzyme activities (GraphPad Prism, MS-Excel) & MS data (Sciex)
Compiling reports and interfacing with collaborators
Coordinating with third-party collaborators for PK study (animal models)
Conducting day-to-day testing and profiling of compounds in cells/protein-based assays
Drafting reports, documenting experiments, and presenting results within the lab and in various forums/meetings
Working closely with other biology group members involved in screening, cell biology, protein biology, and ADME, offering integrated drug discovery support alongside chemistry for multiple client-based projects
Contributing to group activities (like ordering, stocking, and follow-ups, etc.)
Candidate Profile:
M.Sc / M.Pharma (Microbiology/Biotechnology)
1-4 years of working experience with LC-MS/MS, HPLC, bio-analytical studies, etc.
Excellent understanding and knowledge of laboratory tools, techniques, methods, and underlying principles
Hands-on/practical exposure to general biotech laboratory equipment (cell-culture lab, in-vitro and ADME lab)
Excellent theoretical understanding and practical work experience with cell culture techniques (established cell lines), ADME assays (microsomal stability, plasma stability, solubility, permeability, CYP inhibition assays, plasma protein binding assays, etc.)
Ability to overcome technical challenges and exercise sound judgment under pressure
High self-motivation to initiate projects and work independently under aggressive deadlines
Strong technical knowledge with exceptional attention to detail
Excellent personal rapport and ability to engender trust and respect
Ability to work well as part of a small focused team and build relationships
Ability to multitask, recognize problems, and provide input to solutions
Exceptional communication skills and ease in interaction with all stakeholders
Enthusiasm for life, work, and making a difference
Bright, friendly, flexible personality with agility to switch between different skill sets
Exceptional organizational skills that thrive in a fast-paced and vibrant team environment
Positivity, focus, and a winning mentality allied with kindness
Curiosity, energy, creativity, and bravery with a strong desire to help build the o2h culture